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Am J Cardiol. 1999 Aug 15;84(4):462-6, A9.

Histopathologic comparison of human coronary in-stent and post-balloon angioplasty restenotic tissue.

Author information

1
The Gill Heart Institute, University of Kentucky, Lexington, USA. pmoreno@pop.uky.edu

Abstract

Histomorphometric studies for smooth muscle cells, macrophages, tissue factor, collagen, and cell proliferation were performed on 20 atherectomy specimens from patients with in-stent restenosis and 20 specimens from patients with post-balloon PTCA restenosis. Smooth muscle cell content was larger and proliferation index was higher in in-stent restenotic tissue; macrophage, tissue factor, and collagen content were larger in post-balloon percutaneous transluminal coronary angioplasty restenotic tissue, suggesting a more cellular and proliferative response with less thrombogenic potential in human tissue from in-stent restenosis than tissue from post-balloon percutaneous transluminal coronary angioplasty restenosis.

PMID:
10468088
DOI:
10.1016/s0002-9149(99)00334-3
[Indexed for MEDLINE]

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