Format

Send to

Choose Destination
Immunol Res. 1999;20(1):15-27.

Role of cytokines in pulmonary antimicrobial host defense.

Author information

1
Department of Medicine, University of Michigan Medical School, Ann Arbor, USA. tstandif@umich.edu

Abstract

Host defense of the lung is characterized by a fine balance between the generation of a vigorous inflammatory response to clear pathogens and maintenance of the integrity of the alveolar gas-exchange surface. The magnitude of the inflammatory response is therefore tightly regulated by pro- and anti-inflammatory cytokine mediators. This article summarizes current information on the roles of specific cytokines in pneumonia, with particular emphasis on ongoing investigations into the role of innate immunity in bacterial and fungal pneumonia.

PMID:
10467980
DOI:
10.1007/BF02786504
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center