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Cutis. 1999 Aug;64(2):107-9.

Treatment of pyoderma faciale with isotretinoin in a patient with ulcerative colitis.

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Baylor College of Medicine, Houston, Texas, USA.


The explosive onset of fluctuant facial papulonodules, usually in young women, is characteristic of pyoderma faciale. This disorder is neither a true pyoderma nor a variant of acne, but rather a severe form of rosacea. The most effective therapeutic modality appears to be isotretinoin, especially if preceded by a brief course of oral corticosteroids or a short interval of application of potent topical corticosteroids. Despite our concern about the potential adverse effects of systemic retinoids on underlying inflammatory bowel disease, isotretinoin was given to a patient with refractory pyoderma faciale. Response was dramatic, and no ill effects were encountered.

[Indexed for MEDLINE]

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