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Int J Obes Relat Metab Disord. 1999 Jun;23 Suppl 6:S49-50.

The long isoform uncoupling protein-3 (UCP3L) in human energy homeostasis.

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1
Columbia University, College of Physicians and Surgeons, Department of Pediatrics, New York, NY 10032, USA.

Abstract

The biological role(s) proposed for UCP3 in energy homeostasis have been based primarily upon amino acid sequence homology to UCP1. Spontaneous mutations of UCP3> have been described in humans, but not in rodents. The functional consequences-or lack thereof-of these mutations in humans will be of great importance in elucidating the biology of this protein. The results of two such studies are summarized here.

PMID:
10454123
[Indexed for MEDLINE]
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