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Curr Opin Cell Biol. 1999 Aug;11(4):460-5.

Phosphoinositides in membrane traffic.

Author information

  • 1Program in Molecular Medicine, Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA. silvia.corvera@umassmed.edu

Abstract

Phosphoinositides serve as direct local modulators or recruiters of the protein machineries that control membrane trafficking. In the past year, examples of phosphoinositide effectors include regulators of small GTPases in coat assembly, dynamin in clathrin coated vesicle formation and FYVE finger proteins in endocytic membrane traffic. A novel phosphoinositide appears to regulate effectors involved in the formation of multivesicular endosomes.

PMID:
10449332
DOI:
10.1016/S0955-0674(99)80066-0
[PubMed - indexed for MEDLINE]
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