Differential expression of the Drosophila zinc finger gene jim in the follicular epithelium

H Doerflinger; J A Lepesant; C Yanicostas

doi:10.1016/s0925-4773(99)00109-4

Differential expression of the Drosophila zinc finger gene jim in the follicular epithelium

Mech Dev. 1999 Aug;86(1-2):177-82. doi: 10.1016/s0925-4773(99)00109-4.

Authors

H Doerflinger¹, J A Lepesant, C Yanicostas

Affiliation

¹ Institut Jacques Monod, Equipe de Biologie du Développement, UMR 7592, CNRS and Universités Denis-Diderot Paris 7 and Paris 6 Pierre et Marie Curie, 2 place Jussieu, F-75251, Paris Cedex 05, France.

PMID: 10446279
DOI: 10.1016/s0925-4773(99)00109-4

Abstract

The Drosophila gene jim was identified by an enhancer trap line showing asymmetric dorso-ventral expression in the follicular epithelium. It gives rise to the jim-1 and jim-2 transcripts that contain distinct 5'-UTRs but encode the same nine C(2)H(2) zinc finger protein. From stage 10A onward, jim-1 RNA is transcribed in squamous cells while jim-2 RNA is specific to all non-antero-dorsal columnar cells as the result of repression in antero-dorsal cells by the DER pathway.

MeSH terms

Amino Acid Sequence
Animals
Carrier Proteins / genetics*
Carrier Proteins / metabolism
Cloning, Molecular
Drosophila / genetics*
Drosophila Proteins*
Epithelial Cells / cytology
Epithelial Cells / physiology
Female
Gene Expression Regulation, Developmental*
Homozygote
Insect Proteins / genetics
Molecular Sequence Data
Mutation
Ovarian Follicle / cytology
Ovarian Follicle / growth & development*
Ovary / physiology
Rabbits
Sequence Homology, Amino Acid
Transcription Factors*
Transforming Growth Factor alpha*
Transforming Growth Factors / genetics
Zinc Fingers / genetics*

Substances

Carrier Proteins
Drosophila Proteins
Insect Proteins
Jim protein, Drosophila
Transcription Factors
Transforming Growth Factor alpha
grk protein, Drosophila
Transforming Growth Factors

Associated data

GENBANK/AJ133756