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Acta Haematol. 1999;101(4):202-5.

A patient with multiple myeloma, amyloidosis and light-chain deposition disease in kidneys with a long survival.

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Haematology Unit, Department of Internal Medicine, Ioannina Medical School, Ioannina University, Ioannina, Greece.


We report a case of a 39-year-old man with lambda-light-chain multiple myeloma, nephrotic syndrome due to lambda-light-chain deposition disease in kidneys and amyloidosis in other tissues. The patient was treated with melphalan and prednisone for 1 year. After that, he was administered interferon-alpha2b (IFN-alpha2b; 3 MU, 3 times a week) as maintenance therapy for 2 years. At present, 5 years and 6 months after the initial diagnosis, the patient receives IFN-alpha2b (3 MU, twice a week) and remains in complete haematological remission.

[Indexed for MEDLINE]

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