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Trends Microbiol. 1999 Aug;7(8):328-33.

Apicomplexan plastids as drug targets.

Author information

1
Plant Cell Biology Research Center, School of Botany, University of Melbourne, Parkville, VIC 3052, Australia. g.mcgadden@botany.unimelb.edu.au

Abstract

Prokaryotic metabolic pathways in the relict plastid of apicomplexan parasites make this organelle a promising target for drug development. The parasiticidal activity of several herbicides and antibacterial antibiotics is suspected to be a result of their ability to inhibit key plastid activities.

PMID:
10431206
DOI:
10.1016/s0966-842x(99)01547-4
[Indexed for MEDLINE]

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