Format

Send to

Choose Destination
Biochim Biophys Acta. 1999 Jul 30;1439(2):245-63.

Localization and possible functions of phospholipase D isozymes.

Author information

1
Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.

Abstract

The activation of PLD is believed to play an important role in the regulation of cell function and cell fate by extracellular signal molecules. Multiple PLD activities have been characterized in mammalian cells and, more recently, several PLD genes have been cloned. Current evidence indicates that diverse PLD activities are localized in most, if not all, cellular organelles, where they are likely to subserve different functions in signal transduction, membrane vesicle trafficking and cytoskeletal dynamics.

PMID:
10425399
DOI:
10.1016/s1388-1981(99)00098-0
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center