Format

Send to

Choose Destination
Biochim Biophys Acta. 1999 Jul 30;1439(2):175-86.

Mammalian phospholipase D structure and regulation.

Author information

1
Department of Pharmacological Sciences, Institute for Cell and Developmental Biology, SUNY at Stony Brook, Stony Brook, NY 1794-8651, USA. michael@pharm.som.sunysb.edu

Abstract

The recent identification of cDNA clones for phospholipase D1 and 2 has opened the door to new studies on its structure and regulation. PLD activity is encoded by at least two different genes that contain catalytic domains that relate their mechanism of action to phosphodiesterases. In vivo roles for PLD suggest that it may be important for multiple specialized steps in receptor dependent and constitutive processes of secretion, endocytosis, and membrane biogenesis.

PMID:
10425394
DOI:
10.1016/s1388-1981(99)00093-1
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center