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Chest. 1999 Jul;116(1):231-3.

Small airways obstruction syndrome.

Author information

1
Pulmonary Laboratory and Division, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium. Stanescu@pneu.ucl.ac.be

Abstract

STUDY OBJECTIVES:

To clarify the significance of a functional lung pattern characterized by a decreased vital capacity (VC) and an increased residual volume (RV), but with a normal FEV1/VC ratio.

SETTING:

A university teaching hospital.

SUBJECTS:

Patients with bronchial asthma, pulmonary emphysema, and small airways disease, and older subjects.

MEASUREMENTS:

Measurements of static and dynamic lung volumes, diffusing capacity of the lung for carbon monoxide (as measured by the single-breath method), nitrogen slope of the alveolar plateau, and closing volume (as measured by the single-breath O2 test).

CONCLUSION:

A functional pattern characterized by a decreased VC and FEV1 and increased RV, but with a normal FEV1/VC ratio and total lung capacity, reflects an obstructive impairment of small airways.

PMID:
10424530
DOI:
10.1378/chest.116.1.231
[Indexed for MEDLINE]

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