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Chem Biol. 1999 Aug;6(8):R217-24.

Molecular angiogenesis.

Author information

1
Department of Surgery, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. klagsbrun@a1.tch.harvard.edu.

Abstract

New insights into the mechanisms by which blood vessels develop (angiogenesis) have been gained recently, primarily by the identification of factors that inhibit and promote this process. Angiogenesis-stimulating factors are being used to promote growth of new blood vessels in ischemic disease. In contrast, anti-angiogenesis factors are being used as inhibitors of neovascularization to control tumor growth and metastasis.

PMID:
10421764
DOI:
10.1016/S1074-5521(99)80081-7
[Indexed for MEDLINE]
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