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Curr Biol. 1999 Jul 15;9(14):R521-4.

Kinase phosphorylation: Keeping it all in the family.

Author information

1
Howard Hughes Medical Institute, Departments of Chemistry and Chemical Biology and Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Abstract

The identification of PDK1 as a kinase that phosphorylates the AGC family of kinases led to a hunt for 'PDK2', a hypothetical regulated kinase(s) that would be required for full activation of the AGC kinases. Recent findings suggest that the elusive PDK2 may actually be a familiar kinase with an atypical associate.

PMID:
10421571
DOI:
10.1016/s0960-9822(99)80326-1
[Indexed for MEDLINE]
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