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Presse Med. 1999 Jun 26;28(23):1227-30.

[Bacterial concentration in the cerebrospinal fluid in childhood meningitis].

[Article in French]

Author information

1
Service de Microbiologie, Hôpital Robert Debré, Paris.

Abstract

OBJECTIVES:

The aim of this study was to analyze the epidemiological evolution of causal germs in meningitis in children aged 1 day to 15 years and determine the relationship between pretreatment concentrations of bacteria in cerebral spinal fluid (CSF), patient age, bacterial species and bacteriological eradication.

PATIENTS AND METHODS:

A quantitative analysis of germs was performed in 212 children with bacterial meningitis (mean age 19.8 months).

RESULTS:

Bacterial counts ranged from 2.10(1) to 4.10(9) CFU/ml in CSF. Among the 212 patients, 52 (24.5%) had counts 10(7)/ml. Infants had significantly higher counts than the other age groups. Mean counts for Hoemophilus influenzoe serotype B were not different from those for Streptococcus pneumoniae but were significantly higher than for Neisseria meningitidis. Compared with initial germ counts, 98.5% of the CSF specimens were sterile at 24 and 48 hours and 100% at 72 hours.

CONCLUSION:

Germ counts were higher in infants.

PMID:
10420886
[Indexed for MEDLINE]

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