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Zh Vyssh Nerv Deiat Im I P Pavlova. 1999 May-Jun;49(3):400-7.

[The neuronal reactions of the cat motor cortex to electrical stimulation of the ventral tegmental area as a conditioned signal for the reflex of placing the forelimb on a support].

[Article in Russian]

Author information

1
Department of Higher Nervous Activity, Lomonosov State University, Moscow.

Abstract

Electrical stimulation (50-100 pulses, 100-500 Hz) of the ventral tegmental area (VTA) in the vicinity of the n. interpeduncularis in the frontal plane AP2-AP4, L1-L2 caused a cat to grab food placed near its mouth. The conditioned forepaw placing reaction was elaborated using food reinforcement and VTA stimulation as a conditioned stimulus. The conditioned reflex, being once established, was repeatedly performed without extinction in the course of up to 250 trials without food reinforcement. Short (5-10 pulses) conditioned VTA stimulation evoked a prolonged (up to 1000 ms or longer) activation of neurons of the motor cortex and caused a substitution of the inhibitory phase of response to stimulation of the parietal cortex in poststimulus interval in 50-200 ms for the late secondary excitatory response.

PMID:
10420551
[Indexed for MEDLINE]

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