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Curr Opin Chem Biol. 1999 Aug;3(4):459-65.

The development and therapeutic potential of protein kinase inhibitors.

Author information

1
MRC Protein Phosphorylation Unit, Department of Biochemistry, MSI/WTB Complex, Dow Street, University of Dundee, Dundee, DD1 5EH, Scotland, UK. pcohen@bad.dundee.ac.uk

Abstract

A number of small cell-permeant protein kinase inhibitors have been developed that have the potential for treating a variety of diseases. The basis for the specificity of several of these drugs has been elucidated and a number are undergoing human clinical trials.

PMID:
10419844
DOI:
10.1016/S1367-5931(99)80067-2
[Indexed for MEDLINE]

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