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Acta Paediatr. 1999 Jun;88(6):595-7.

Oral bedtime cornstarch supplementation reduces the risk for nocturnal hypoglycaemia in young children with type 1 diabetes.

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Department of Paediatrics, Orebro Medical Centre Hospital, Sweden.


The effect of oral cornstarch supplementation was evaluated in 14 pre-school children with type 1 diabetes in a randomized, double-blind, placebo-controlled trial. The children received cornstarch (0.3 g/kg) or placebo at bedtime on five occasions each, and their blood glucose concentrations were measured at bedtime, at 02.00 h and in the morning. The mean nocturnal blood glucose concentration (at 02.00 h) was 2.2 mmol/L higher and the number of blood glucose concentrations below 5 mmol/L were reduced by 64% when cornstarch had been ingested at bedtime. We conclude that cornstarch may be used in pre-school children with type 1 diabetes to reduce the risk for nocturnal hypoglycaemia.

[Indexed for MEDLINE]

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