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Ann N Y Acad Sci. 1999 Jun 21;881:445-51.

Plasma agmatine and platelet imidazoline receptors in depression.

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1
Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson 39216-4505, USA. AHalaris@psychiatry.umsmed.edu

Abstract

Plasma agmatine concentrations are elevated significantly in depressed patients compared to healthy controls. Treatment with the antidepressant bupropion normalized plasma agmatine levels. Correlational evidence is presented that a change in plasma agmatine levels may lead to similar changes in platelet I1 imidazoline receptors.

PMID:
10415948
[Indexed for MEDLINE]
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