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Ann N Y Acad Sci. 1999 May 18;870:68-80.

Mobile gene cassettes and integrons in evolution.

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Sydney Laboratory, NSW, Australia.


Integrons and the site-specific recombination systems encoded by them provide a simple mechanism for the addition of new genes to bacterial chromosomes. Although there is substantial divergence among the four known integron-encoded integrases, they all recognize the recombination sites, known as 59-base elements, that are associated with genes that are packaged in gene cassettes. In contrast, the integron-associated recombination sites, attl sites, are preferentially recognized by the cognate integrase.

[Indexed for MEDLINE]

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