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Kidney Int. 1999 Jul;56(1):333-7.

The course of the remnant kidney model in mice.

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Department of Medicine, School of Medicine, University of Minnesota, Minneapolis 55455, USA.


The remnant kidney model was produced in mice by unilateral nephrectomy and partial infarction of the remaining kidney. Control mice underwent laparotomy only. The mice were studied for up to 44 weeks. No quantitative differences were noted in systolic arterial pressure, proteinuria, or histopathology between control mice and those with a remnant kidney. Glomerular enlargement occurred in the remnant kidney.

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