Format

Send to

Choose Destination
J Pathol. 1999 Feb;187(3):272-8.

The transition from hyperplasia to invasive carcinoma of the breast.

Author information

1
Department of Histopathology, University College London Medical School, U.K. s.lakhani@ucl.ac.uk

Abstract

The multistep model of carcinogenesis in the breast suggests a transition from normal epithelium to invasive carcinoma via non-atypical and atypical hyperplasia and in situ carcinoma. Within the breast, these proliferations are heterogeneous in their cytological and architectural characteristics. This review considers the evidence supporting a precursor role for these preinvasive lesions.

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center