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Curr Opin Neurobiol. 1999 Jun;9(3):329-35.

Assembly of signaling machinery at the postsynaptic membrane.

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Department of Anatomy & Cellular Neurobiology, University of Ulm, Albert-Einstein-Allee 11, 89069, Ulm, Germany.


The postsynaptic membrane and the subsynaptic cell compartment are specialized for inter- and intracellular signaling. Recent work has focused on the role of synaptic activity in regulating the surface distribution of neurotransmitter receptors. In addition, several components of secondary signaling pathways involved in the long-term regulation of synaptic efficacy have been identified.

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