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Curr Opin Cell Biol. 1999 Jun;11(3):372-7.

Nuclear organization of pre-mRNA splicing factors.

Author information

1
Department of Biochemistry, University of Dundee, Medical Sciences Institute/Wellcome Trust Building Complex, Dow Street, Dundee, DD1 5EH,UK.

Abstract

The splicing of mRNA precursors (pre-mRNA) in the nucleus is catalyzed by a complex machinery termed the spliceosome. In order to understand how it functions in vivo, it is essential to complement biochemical analyses with a detailed study of how spliceosome components are organized within the nucleus.

PMID:
10395556
DOI:
10.1016/S0955-0674(99)80052-0
[Indexed for MEDLINE]

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