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Immunol Today. 1999 Jul;20(7):330-5.

T-cell function in newborn mice and humans.

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Dept of Microbiology and Immunology, University of Miami Medical School, Miami, FL 33136, USA.


Neonates mount poor immune responses, and it has been assumed that neonatal T cells differ qualitatively from adult T cells. Here, Becky Adkins discusses this issue in the light of recent data indicating that T cells in neonates are developmentally mature in their capacity to mount protective Th1-type and cytotoxic T lymphocyte responses.

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[Indexed for MEDLINE]

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