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Curr Opin Genet Dev. 1999 Jun;9(3):321-7.

Development of the mammalian enteric nervous system.

Author information

1
Division of Developmental Neurobiology Medical Research Council National Institute for Medical Research The Ridgeway, Mill Hill, London, NW71AA, UK.

Abstract

The mammalian enteric nervous system is derived from neural crest cells which invade the foregut and hindgut mesenchyme. It has been established that signalling molecules produced by the mesenchyme of the gut wall play a critical role in the development of the mammalian enteric nervous system. Recent studies have characterised further the role of such molecules and have identified novel extracellular and intracellular signals that are critical for enteric ganglia formation.

PMID:
10377293
DOI:
10.1016/s0959-437x(99)80048-3
[Indexed for MEDLINE]

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