Format

Send to

Choose Destination
Curr Opin Immunol. 1999 Jun;11(3):256-64.

Signal transduction from the B cell antigen-receptor.

Author information

1
Fox Chase Cancer Center, Institute for Cancer Research, Division of Basic Science, 7701 Burholme Avenue, Philadelphia, PA 19111, USA. ksvcampbell@fccc.edu.

Abstract

Ligation of the B cell antigen-receptor triggers an intricate maze of intercalated biochemical events that ultimately affect B cell biological responses. Recent advances have helped to connect many loose ends by identifying key adaptor proteins, such as BLNK/SLP-65, defining crucial roles for phosphatidylinositol-3-kinase and mapping pathways controlling the mitogen-activated protein kinases (ERK, JNK and p38).

PMID:
10375554
DOI:
10.1016/s0952-7915(99)80042-9
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center