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Curr Opin Immunol. 1999 Jun;11(3):249-55.

Co-receptors on B lymphocytes.

Author information

1
Department of Immunology, Medical Research Institute, Tokyo Medical andDental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan. tsubata.imm@mri.tmd.ac.jp

Abstract

Co-receptors have been shown to regulate the antigen-receptor signaling threshold for B cell responses by modulating the activation of signaling molecules that are essential for transmitting a signal through the antigen-receptor. Co-receptors appear to modulate the signaling threshold for B cell tolerance distinctly from that for B cell activation.

PMID:
10375550
DOI:
10.1016/s0952-7915(99)80041-7
[Indexed for MEDLINE]

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