Format

Send to

Choose Destination
Am J Surg. 1999 May;177(5):437-40.

Respiratory failure following talc pleurodesis.

Author information

1
Department of Surgery, Swedish Medical Center, Seattle, Washington, USA.

Abstract

BACKGROUND:

Sterile talc is currently the agent of choice for pleurodesis. Its success rate is excellent, and talc is generally well tolerated. However, a recent experience with fulminant pneumonitis following talc pleurodesis prompted a review of our experience.

METHODS:

A retrospective review of patients undergoing talc pleurodesis at our institution between December 1993 and December 1997 was performed, documenting respiratory and other complications. Statistical analysis was performed using Student's t test and Pearson correlations.

RESULTS:

Seventy-eight patients received 89 talc pleurodesis procedures. Respiratory complications or death occurred in 33%; 9% of patients developed adult respiratory distress syndrome. There was no statistical difference in outcomes between patient groups, methods of application, or talc dosages utilized.

CONCLUSIONS:

This series revealed a significantly higher rate of serious complications than that reported in the current literature, without implicating a clear reason for these outcomes. Our data raise questions about the safety of talc pleurodesis.

PMID:
10365887
DOI:
10.1016/s0002-9610(99)00075-6
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center