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J Virol. 1999 Jul;73(7):6114-6.

Retroviral vectors pseudotyped with lymphocytic choriomeningitis virus.

Author information

1
Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie an der Universität Hamburg, 20251 Hamburg, Germany.

Abstract

Pseudotyping can improve retroviral vector stability and transduction efficiency. Here, we describe a novel pseudotype of murine leukemia virus packaged with lymphocytic choriomeningitis virus (LCMV). This pseudotype was stable during ultracentrifugation and infected several cell lines from different species. Moreover, LCMV glycoproteins were not cell toxic.

PMID:
10364368
PMCID:
PMC112677
[Indexed for MEDLINE]
Free PMC Article

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