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Curr Opin Biotechnol. 1999 Jun;10(3):279-85.

Perspectives of medium chain length poly(hydroxyalkanoates), a versatile set of bacterial bioplastics

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Institute of Biotechnology ETH Zurich Honggerberg HPT 8093, Zurich, Switzerland.


Medium chain length (mcl) poly(hydroxyalkanoic acids) (PHAs) are polyesters accumulated by fluorescent Pseudomonads and other bacteria. Work on the genetics of mcl-PHA formation has led to polymer synthesis in recombinant bacteria and plants. Several high and medium cost applications are now emerging. With optimized bacterial mcl-PHA synthesis on inexpensive agro-substrates and the development of plant-based mcl-PHAs in the next decade, the production economics of these bioplastics will ultimately permit their sustainable production for bulk applications.

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