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Bioorg Med Chem Lett. 1999 May 17;9(10):1391-4.

Short synthesis and anti-rhinoviral activity of imidazo[1,2-a]pyridines: the effect of acyl groups at 3-position.

Author information

1
Centro de Investigación Lilly S.A., Alcobendas (Madrid)-Spain. hamdouchi_chafiq@lilly.com

Abstract

Various 2-amino-3-acyl-6-[(E)-1-phenyl-2-N-methylcarbamoylvinyl]-imidazo[1 ,2-a]pyridines, structurally related to Enviroxime were prepared to determine the effect of acyl groups on the anti-rhinoviral activity. A short and efficient means for the construction of the imidazo nucleus as well as biological evaluation of the final compounds are disclosed.

PMID:
10360742
DOI:
10.1016/s0960-894x(99)00193-6
[Indexed for MEDLINE]

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