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Curr Biol. 1999 Jun 3;9(11):R416-8.

Biological sensors: More than one way to sense oxygen.

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Department of Molecular Biology, Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.


Recently determined structures of the oxygen-sensing heme domain of the bacterial protein FixL have revealed a new binding environment and signal transduction mechanism for heme; they have also provided new insights into the diverse 'PAS' domain superfamily.

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