Carbamazepine hypersensitivity and the use of lymphocyte proliferation responses

K L Brown; D C Henderson; S Nadel; A Tanveer; R Booy

doi:10.1017/s0012162299000560

Carbamazepine hypersensitivity and the use of lymphocyte proliferation responses

Dev Med Child Neurol. 1999 Apr;41(4):267-9. doi: 10.1017/s0012162299000560.

Authors

K L Brown¹, D C Henderson, S Nadel, A Tanveer, R Booy

Affiliation

¹ Department of Paediatrics, St Mary's Hospital Medical School, London, UK.

PMID: 10355812
DOI: 10.1017/s0012162299000560

Abstract

This report describes a case of multisystem failure in a 5-year-old boy who was being treated with carbamazepine for a seizure disorder. Carbamazepine hypersensitivity was diagnosed from the combination of the clinical constellation and the results of the patient's peripheral blood monocyte proliferation responses to both carbamazepine and a panel of other medications.

Publication types

Case Reports

MeSH terms

Anticonvulsants / adverse effects*
Carbamazepine / adverse effects*
Cell Division / drug effects
Child, Preschool
Drug Hypersensitivity / etiology*
Drug Hypersensitivity / immunology
Epilepsy, Tonic-Clonic / drug therapy
Humans
Lymphocytes / drug effects*
Male

Substances

Anticonvulsants
Carbamazepine