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Immunol Today. 1999 Jun;20(6):262-6.

T-cell clonality in immune responses.

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Dept of Sexually Transmitted Diseases, Royal Free and University College Medical School, Mortimer Market off Capper St, London, UK WC1E 6AU.


Recent methodological advances allow the analysis of clonal composition within T-cell subsets. Here, Mala Maini and colleagues review the available data on clonality in acute immune responses and steady-state situations. They highlight and explore reasons for the striking differences in clonality between the CD4+ and CD8+ T-cell subsets.

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[Indexed for MEDLINE]

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