Send to

Choose Destination
Biochem Cell Biol. 1998;76(5):735-41.

Regulation and characterization of the Na+/H+ exchanger.

Author information

Department of Biochemistry, University of Alberta, Edmonton, Canada.


The Na+/H+ exchanger is a ubiquitous protein present in all mammalian cell types that functions to remove one intracellular H+ for one extracellular Na+. Several isoforms of the protein exist, which are referred to as NHE1 to NHE6 (for Na+/H+ exchanger one through six). The NHE1 protein was the first isoform cloned and studied in a variety of systems. This review summarizes recent papers on this protein, particularly those that have examined regulation of the protein and its expression and activity.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center