Format

Send to

Choose Destination
See comment in PubMed Commons below
Eur J Hum Genet. 1999 May-Jun;7(4):435-46.

Human-specific insertion/deletion polymorphisms in Indian populations and their possible evolutionary implications.

Author information

1
Anthropology and Human Genetics Unit, Indian Statistical Institute, Calcutta, India. ppm@isical.ac.in

Abstract

DNA samples from 396 unrelated individuals belonging to 14 ethnic populations of India, inhabiting various geographical locations and occupying various positions in the socio-cultural hierarchy, were analysed in respect of 8 human-specific polymorphic insertion/deletion loci. All loci, except Alu CD4, were found to be highly polymorphic in all populations. The levels of average heterozygosities were found to be very high in all populations and, in most populations, also higher than those predicted by the island model of population structure. The coefficient of gene differentiation among Indian populations was found to be higher than populations in most other global regions, except Africa. These results are discussed in the light of two possible scenarios of evolution of Indian populations in the broader context of human evolution.

PMID:
10352934
DOI:
10.1038/sj.ejhg.5200317
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Support Center