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Age Ageing. 1999 Mar;28(2):99-102.

Accuracy of diagnosis in patients with presumed Parkinson's disease.

Author information

1
University Department of Geriatric Medicine, Glan Clwyd Hospital, Rhyl, North Wales, UK.

Abstract

OBJECTIVES:

to study the diagnostic accuracy for parkinsonism and Parkinson's disease in a community-based sample of subjects on anti-parkinsonian medication.

METHODS:

computerized prescribing records in general practice were used to create a community-based disease register for Parkinson's disease. Subjects were examined to establish the likely diagnosis using recommended clinical diagnostic criteria.

RESULTS:

of 402 cases, parkinsonism was confirmed in 74% and clinically probable Parkinson's disease in 53%. The commonest causes of misdiagnosis were essential tremor, Alzheimer's disease and vascular pseudo-parkinsonism. Over one-quarter of subjects did not benefit from anti-parkinsonian medication.

CONCLUSIONS:

there is difficulty in diagnosing parkinsonism and Parkinson's disease in elderly subjects and we suggest early referral of those suspected of having parkinsonism for specialist assessment.

PMID:
10350403
DOI:
10.1093/ageing/28.2.99
[Indexed for MEDLINE]

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