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Curr Biol. 1999 May 20;9(10):R364-7.

Signal transduction: Gyrating protein kinases.

Author information

1
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA.

Abstract

Recently determined structures have linked histidine kinases with class II topoisomerases, the DNA repair enzyme MutL and the molecular chaperone Hsp90. This surprising finding may foreshadow a shift in our understanding of energy coupling mechanisms in signal transduction networks.

PMID:
10339418
DOI:
10.1016/s0960-9822(99)80228-0
[Indexed for MEDLINE]
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