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Chest. 1999 May;115(5):1259-64.

The association between occupation and asthma in general medical practice.

Author information

1
Department of Medicine, University of California at San Francisco, 94143-0924, USA. blancp@itsa.ucsf.edu

Abstract

BACKGROUND:

In general practice settings, the proportion of adult asthma attributable to occupational factors is not known.

OBJECTIVE:

The goal of this study was to estimate the proportion of adult asthma cases that can be attributed to occupational factors initiating new disease onset and exacerbating preexisting disease.

METHODS:

We performed a cross-sectional analysis of interview data for 150 adults with asthma recruited from a random sample of family practice specialists. We ascertained the asthma and work histories of the subjects and estimated the proportion with likely work-initiated asthma and work-related asthma recrudescence.

RESULTS:

Seventy-four subjects (49%) reported adult-onset asthma while employed; an additional 25 (17%) reported recrudescence of previously quiescent childhood-onset asthma during employment. Of those with new-onset asthma while employed, 15 (10% of the study group; 95% confidence interval, 5 to 15%) were employed in occupations at increased risk of occupational asthma initiation on the basis of an independent job scoring matrix. Of those with asthma recrudescence in adulthood, seven (5% of the study group; 95% confidence interval, 2 to 8%) were employed in occupations at increased risk of exposures aggravating asthma.

CONCLUSIONS:

Among adults with asthma treated in general practice settings, > 1 in 10 patients has a work history strongly suggestive of a potential relationship between exposure and disease.

Comment in

PMID:
10334137
DOI:
10.1378/chest.115.5.1259
[Indexed for MEDLINE]

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