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J Cataract Refract Surg. 1999 May;25(5):648-51.

Systemic levels of lidocaine after intracameral injection during cataract surgery.

Author information

1
Augenklinik, Medizinische Universität zu Lübeck, Germany.

Abstract

PURPOSE:

To evaluate the systemic concentrations of lidocaine after intracameral injection of a 1% solution during cataract surgery and the safety of this application mode.

SETTING:

Department of Ophthalmology, Medical University of Lübeck, Lübeck, Germany.

METHODS:

This prospective study included 10 patients who had phacoemulsification and posterior chamber lens implantation with a self-sealing scleral tunnel incision. Topical anesthesia was achieved using cocaine 10% eyedrops combined with 0.5mL of unpreserved lidocaine 1% injected into the anterior chamber. Blood samples were taken from all patients at predetermined intervals before and during the procedure. Consecutive analysis for lidocaine was performed with gas chromatography.

RESULTS:

In all samples, serum lidocaine concentrations were below a minimum detectable level of 100 ng/mL. No local or systemic intraoperative or postoperative complications were noted.

CONCLUSIONS:

Intracameral injection of 0.5 mL lidocaine 1% revealed no systemic therapeutic concentrations. In patients in whom other forms of needle-delivered local anesthesia are contraindicated, intracameral injection of lidocaine should be considered to enhance topical anesthesia.

PMID:
10330639
DOI:
10.1016/s0886-3350(99)00005-x
[Indexed for MEDLINE]

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