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Curr Biol. 1999 May 6;9(9):R332-5.

Endocytosis: an assembly protein for clathrin cages.

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1
MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK.

Abstract

The protein AP180 is known to have clathrin-assembly activity in vitro. AP180 has now been found to be crucial for synaptic vesicle endocytosis and the maintenance of a uniform-size vesicle population in vivo. These results significantly advance our understanding of clathrin-mediated endocytosis in the synapse and elsewhere.

PMID:
10330371
DOI:
10.1016/s0960-9822(99)80206-1
[Indexed for MEDLINE]
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