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Stat Med. 1999 Apr 15;18(7):787-98.

A multiple comparison procedure for three- and four-armed controlled clinical trials.

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National Heart, Lung, and Blood Institute, Rockledge II Center, Bethesda, MD 20892-7938, USA.


Multi-armed controlled trials are becoming increasingly popular. With them comes the issue of how to deal with the possibility of multiple Type I errors. This paper recommends a simple and appealing method for three- and four-armed trials in which one is a control. This article is a US Government work and is in the public domain in the United States.

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