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[Clinical observation on treatment of infantile cholestatic hepatitis syndrome by rhubarb].

[Article in Chinese]

Author information

1
Department of Pediatrics, Tongji Hospital, Tongji Medical University, Wuhan.

Abstract

OBJECTIVE:

To evaluate the role of Rhubarb in treating infantile cholestatic hepatitis syndrome (IHS).

METHODS:

Forty-four patients of the treatment group were treated with Rhubarb per os and/or duodenal infusion, 20 cases of the control group were treated with general liver protecting therapy such as inosine, vitamin C and glucose. Serum bilirubin, alanine transaminase (ALT) and gamma-glutamyl transferase (gamma-GT) level, bilirubin in duodenal juice and liver size were observed before and after treatment.

RESULTS:

In the treatment group, 18 cases were markedly effective, 21 effective, 3 ineffective and 2 were deteriorated, while in the control group, the respective number were 0, 4, 13 and 3.

CONCLUSIONS:

Rhubarb was a markedly effective in cholagoging and abating of jaundice, it could promote the recovery of liver function, dredge the cholestasis in cholangiole and micro-cholangiole so as to promote the bile secretion.

PMID:
10322829
[Indexed for MEDLINE]

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