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Curr Biol. 1999 May 6;9(9):R342-5.

T-cell development: a role for self-peptides in positive selection.

Author information

1
Section of Immunobiology, Yale University School of Medicine, The Howard Hughes Medical Institute, New Haven, Connecticut, 06520-8011, USA.

Abstract

An important issue for immunologists is the difference between the two main processes that determine the mature repertoire of T-cell receptors, termed positive and negative selection. Recent papers have addressed the role of self-peptides in the process of positive selection.

PMID:
10322106
DOI:
10.1016/s0960-9822(99)80209-7
[Indexed for MEDLINE]
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