Send to

Choose Destination
Int Clin Psychopharmacol. 1999 Mar;14(2):133-7.

Clinical trials of new antipsychotics: a critical appraisal.

Author information

Laboratory of Epidemiology and Social Psychiatry, WHO Collaborating Centre for Research and Training in Mental Health, Mario Negri Institute for Pharmacological Research, Milan, Italy.


In recent years the efficacy of new antipsychotics has been investigated through a number of randomized controlled trials. This paper considers some methodological flaws that affect these studies and proposes possible solutions. The final goal is the implementation of a new generation of trials with the aim of demonstrating superiority of effect of the new antipsychotic over the reference one.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center