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Radiology. 1999 Mar;210(3):851-7.

Lung air spaces: MR imaging evaluation with hyperpolarized 3He gas.

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Department of Radiology, University of Virginia Health Sciences Center, Charlottesville 22908, USA.


Thirty-two magnetic resonance imaging examinations of the lungs were performed in 16 subjects after inhalation of 1-2 L of helium 3 gas that was laser polarized to 10%-25%. The distribution of the gas was generally uniform, with visualization of the fissures in most cases. Ventilation defects were demonstrated in smokers and in a subject with allergies. The technique has potential for evaluating small airways disease.

[Indexed for MEDLINE]

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