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Radiology. 1999 Feb;210(2):325-32.

Lung transplantation for lymphangioleiomyomatosis: role of imaging in the assessment of complications related to the underlying disease.

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1
Department of Radiology, University of Wisconsin Hospital and Clinics, Madison 53792-3252, USA.

Abstract

PURPOSE:

To identify the complications and imaging findings related to lymphangioleiomyomatosis (LAM) after lung transplantation.

MATERIALS AND METHODS:

The authors retrospectively reviewed the clinical histories and imaging studies of 13 patients from five major medical centers who underwent unilateral (n = 8) or bilateral (n = 5) lung transplantation for LAM between 1991 and 1997. Complications related to LAM, both before and after transplantation, were recorded.

RESULTS:

The following LAM-related complications were found during and after transplantation: excessive pleural adhesions (n = 4), native lung pneumothorax (n = 3), chylous effusion (n = 1), chylous ascites (n = 3), complications from renal angiomyolipomas (n = 4), and recurrent LAM (n = 1). Diagnosis could be made or suggested with computed tomography (CT) in all cases. Four patients (31%) died; one patient died of complications of LAM.

CONCLUSIONS:

Patients who have undergone lung transplantation for LAM have increased morbidity and mortality due to complications related to their underlying disease. These LAM-related complications can be diagnosed or suggested with CT.

[Indexed for MEDLINE]

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