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Eur J Obstet Gynecol Reprod Biol. 1999 Feb;82(2):191-4.

Pregnancy and multiple sclerosis: a 2-year experience.

Author information

1
Department of Obstetrics and Gynecology, Rabin Medical Center, Petah Tiqva, Israel.

Abstract

OBJECTIVE:

To present our experience with management of parturients with multiple sclerosis and to examine the role of intravenous immunoglobulin (IVIg) in the prevention of postpartum exacerbations of the disease.

METHODS:

Fifteen patients with multiple sclerosis with a relapsing-remitting course were followed during pregnancy and 6 months postpartum. To prevent postpartum exacerbations, 14 of the patients had received IVIg after delivery.

RESULTS:

None of the patients who received postpartum IVIg relapsed during the 6 months after delivery. None of the observed obstetric complications nor the operative deliveries could be related to the coexistence of multiple sclerosis.

CONCLUSION:

Postpartum IVIg treatment is beneficial in preventing acute childbirth-associated exacerbations in patients with relapsing-remitting multiple sclerosis. Furthermore, this disease does not seem to increase obstetric complications.

PMID:
10206414
DOI:
10.1016/s0301-2115(98)00231-0
[Indexed for MEDLINE]

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