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Trends Microbiol. 1999 Mar;7(3):124-8.

Domain organization and oligomerization among H-NS-like nucleoid-associated proteins in bacteria.

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Dept of Microbiology, Moyne Institute of Preventive Medicine, University of Dublin, Trinity College, Ireland.


The bacterial nucleoid-associated proteins H-NS and StpA can form homomeric or heteromeric complexes, a parallel with protein HU. Thus, functional modulation of H-NS and StpA by one another and by other proteins with appropriate interaction domains is possible. This has implications for bacterial pathogenesis and adaptation to environmental stress.

[Indexed for MEDLINE]

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