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Trends Microbiol. 1999 Mar;7(3):115-20.

Signalling pathways in two-component phosphorelay systems.

Author information

1
Lehrstuhl für Mikrobiologie, Theodor-Boveri-Institut, Universität Würzburg, Germany.

Abstract

Two-component systems are characterized by phosphotransfer reactions involving histidine and aspartate residues in highly conserved signalling domains. Although the basic principles of signal transduction by these systems have been elucidated, several important aspects, such as their integration into more complex cellular regulatory networks and the molecular basis of the specificity of signal transduction, remain unknown.

PMID:
10203840
DOI:
10.1016/s0966-842x(99)01458-4
[Indexed for MEDLINE]

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